Comino is located in between Malta and Gozo and can be reached by a regular ferry service provided by United Comino Ferries www.UnitedCominoFerries.com leaving from Äirkewwa on the north-western tip of Malta - the same place that the much larger ferries to Gozo depart from or from Mgarr in Gozo. The Comino Hotel also offers a shuttle service for it's guests. Sailings are irregular - check with the Comino Hotel.
Many tourist boats from both Malta and Gozo head for the Blue Lagoon on a daily basis. Some smaller craft use a landing platform halfway between the Blue and Crystal Lagoons, which can be an energetic walk and perhaps best missed if you are not keen on walking on rough tracks.